Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric
protein secreted by a variety of vascularized tissues.The reported activities of VEGF include
stimulation of endothelial cell growth, angiogenesis, and capillary
permeability. Human VEGF-165 is a 43 kDa homodimeric protein consisting of two 165 amino acid
Yeast Pichia pastoris.
Greater than 90% by SDS-PAGE.
The biological activity of yeast expressed VEGF was determined by its mitogenic activity on arterial endothelial cell (CPAE). Mitogenic activity was obtained in a concentration range
of 20 ng/ml to 500 ng/ml.
White lyophilized powder or adequate solution.
The lyophilized powder, though stable at room temperature, is best stored
desiccated below 0 °C. It should be reconstituted with sterile water to a
concentration of 100 mg/ml.
This solution can be diluted with water or other buffered solutions.
Reconstituted human VEGF can be stored in undiluted aliquots at -20 °C for up
to six months.